Package: influential Type: Package Title: Identification and Classification of the Most Influential Nodes Language: en-US Version: 2.3.1.9000 Authors@R: c( person("Adrian", "Salavaty", role = c("aut", "cre"), email = "abbas.salavaty@gmail.com", comment = c(ORCID = "0000-0001-9320-5889")), person("Mirana", "Ramialison", role = "ths"), person(c("Peter", "D."), "Currie", role = "ths") ) Description: Provides functions for the identification, classification, and ranking of influential nodes and candidate features from network and omics data. The package implements the Integrated Value of Influence (IVI) for integrative network centrality analysis, the SIR-based Influence Ranking (SIRIR) model for unsupervised influence ranking, and the Experimental data-based Integrative Ranking (ExIR) model for prioritizing candidate driver, biomarker, and mediator features from experimental omics data. Functions are provided for network reconstruction from adjacency matrices and data frames, topological analysis, centrality calculation, assessment of associations between centrality measures, and conditional probability analysis. ExIR supports bulk and single-cell omics data, including matrices, sparse matrices, data frames, tibbles, and Seurat objects. Imports: igraph, irlba, edgeR, cli, Matrix, SeuratObject, tibble, janitor, ranger, foreach, doParallel, ggplot2, Rcpp LinkingTo: Rcpp Suggests: Hmisc (>= 4.3-0), mgcv (>= 1.8-31), nortest (>= 1.0-4), NNS (>= 0.4.7.1), BiocManager, readr, shiny, shinythemes, shinyWidgets, shinyjs, shinycssloaders, colourpicker, magrittr, DT, knitr, rmarkdown Depends: R (>= 4.0.0) Additional_repositories: https://bioconductor.org/packages/release/bioc URL: https://github.com/asalavaty/influential, https://asalavaty.github.io/influential/ BugReports: https://github.com/asalavaty/influential/issues License: GPL-3 Encoding: UTF-8 LazyData: true RoxygenNote: 7.3.3 VignetteBuilder: knitr Config/pak/sysreqs: libglpk-dev libicu-dev libxml2-dev Repository: https://asalavaty.r-universe.dev Date/Publication: 2026-06-11 04:05:33 UTC RemoteUrl: https://github.com/asalavaty/influential RemoteRef: HEAD RemoteSha: 5f4ef13a0c0d97ba7686caf054d728487bd2aad3 NeedsCompilation: yes Packaged: 2026-06-11 05:31:25 UTC; root Author: Adrian Salavaty [aut, cre] (ORCID: ), Mirana Ramialison [ths], Peter D. Currie [ths] Maintainer: Adrian Salavaty